The Brilliance and Aptitude of Dr. Mark Holterman

Doctor, Medical Professional


Dr. Mark Holterman is a world-renowned Pediatric surgeon and innovator in global health. From his humble beginnings in a Wisconsin farm, Dr. Mark Holterman climbed the ladder of success to ultimately become one of the world’s best Pediatric surgeons. In addition to his career as a doctor, Dr. Mark Holterman is the Chief Executive Officer (CEO) of Mariam Global Health, and he has been a practicing physician for decades. Dr. Mark Holterman is a one of a kind doctor who is working on changing the world, and the world of medicine alike.



The Life and Times of Dr. Mark Holterman

Dr. Mark Holterman gained his love of medicine from a more than spectacular educational background. Dr. Mark Holterman studied biology at Yale University where he graduated with honors (cum laude) in 1980. After his Ivy League undergraduate work, Dr. Mark Holterman set his sights on medical school. Upon graduation, Mark Holterman, before he became Dr. Mark Holterman, received an NIH scholarship in the Medical Scientist Training program. He was able to use the scholarship to attend the University of Virginia (UVA) for a program that allowed him to earn not only his Medical Doctor (MD) degree but his Ph.D. as well. After thirteen years at the University of Virginia, Dr. Mark Holterman had studied medicine and immunology, finished his residency in general surgery, gotten married to Axuan, another surgeon and sciencewiz, and most importantly, become the father to two beautiful sons. While in Montreal, Dr. Mark Holterman flexed his immunology muscles that he gained from his time in medicinal school by conducting immunology research at the Clinical Institute of Montreal.



Dr. Mark Holterman became an instructor of surgery from 1993 to 1995 at the University of Washington. During this time, Dr. Mark Holterman was also completing his fellowship in Pediatric Surgery at Seattle Children’s Hospital (Vitals). In 1995, the family, now with a third son, moved to Montreal, Canada so Dr. Axuan Holterman could also train in Pediatric Surgery. After the stint in Montreal, the dynamic doctor duo moved to Chicago in 1997 where they would work as physicians and as instructors at the University of Illinois College of Medicine. For thirteen years, Dr. Mark Holterman developed basic and translational research programs at the University of Illinois.


Dr. Mark Holterman’s career as a doctor cannot be understated. He has had decades of experience working a Pediatric Surgeon all over the globe.

  • Mark Holterman worked as the chief surgeon for two years at Advocate Children’s Hospital in Oak Lawn, Illinois.
  • Mark Holterman worked as the Attending Pediatric Surgeon at Rush University Medical Center from August of 2000, to July 2012.
  • Mark Holterman served as a Pediatric Surgeon in the Children’s Hospital of OSF Healthcare


Currently, Dr. Mark Holterman serves as the CEO and Chief Medical Officer of Mariam Global Health, a company he founded to invest in businesses in order to make an impact on global health, where he has worked for five years as an opportunistic venture capitalist investing in the newest technology for medicine.


Dr. Mark Holterman through Mariam Global Health has financed and founded companies in oncology, regenerative medicine, stem cell therapy and medical devices. Since studying immunology in medical school, Dr. Mark Holterman has a vested interest in autoimmunity, obesity and stem cell medicine. Consulting with venture capital companies.

Impact Innovators and Investors

After 40 years doing nothing but living and breathing science and medicine, Dr. Mark Holterman has a chance to use his talent and connections to radically impact healthcare. These “impact innovators” don’t have the business or financial resources to make their scientific dreams come true. That is where Dr. Mark Holterman and Mariam Global Health step in. They save these innovations from dying before they get a chance to thrive.

In addition to impact innovators, impact investors understand the financial aspects of Global Health, and desire to make a difference with their money.

Mariam Global Health serves as :

  • a talent scout
    • Looks for impact innovators to invest in to advance global health
  • a coach to advance venture capitalists with ideas on how to invest in global health technology
    • Teaches companies how to do things such as build their business, secure the IP, and early financing
  • business agent
    • ensuring the greatest financial return for the technology
  • Recruiter for foreign talent
    • Get impact innovators access to the developmental help they need to start their work
    • Look for global collaborators for clinical trials, technology deployment, and product distribution


Advice from Dr. Mark Holterman

Dr. Mark Holterman starts and ends every day with a prayer. He is flexible with his work schedule and attentive to the needs that come up from a natural financial problem. Dr. Mark Holterman advises that leaders delegate work so as not to get too overwhelmed. In order to continuously advance one’s business, Dr. Mark Holterman advises that business look outside areas of their specialty to help them continue to grow (

When trying to bring a new idea to life, Dr. Mark Holterman reality-checks himself to make sure he is getting into a successful situation.


Some outcomes of a reality-checking situation could be

  • the ide is outdated
  • Someone else has the same idea
  • Not enough demand for the idea
  • The idea would take too long to develop
  • It would be a huge success!!!

Dr. Mark Holterman knows to look to the experts in the field of work he is researching and to make sure he doesn’t get greedy when working on new technology. He also knows how important self-care is when working in medicine, so he makes sure to tell people to sleep and shower as well as work.


Dr. Mark Holterman knows the necessity of not falling prey to ego, and to make sure ideas are taken care of well but not treated as indispensable.


Dr. Mark Holterman recommends avoiding group think when pursuing ideas for business. It is important to find a trusted team and a group of experts to run ideas past.


Dr. Mark Holterman knows how important it is to run a company lean, hungry, and efficiently. Dr. Mark Holterman has actually gotten lucky when investors have backed out of deals because he knows how much money would’ve been wasted on ideas that would not have been successful.



Dr. Mark Holterman knows business and medicine. He is helping make the world a better place with the innovations of Mariam Global Health. He has saved countless lives, and his sense in business has helped advance medical technology. A forty year medical career has helped Dr. Mark Holterman become a preeminent voice in medicine and technology.

More about Dr. Mark Holterman on LinkedIn and Crunchbase

Leave a Reply